Objective: The etiology, clinical manifestations and treatment of 1170 patients\nwith symptomatic epilepsy were retrospectively analyzed and provided\nguidance for further treatment of symptomatic epilepsy. Method: A retrospective\nanalysis of 1170 cases of symptomatic epilepsy admitted to the First\nAffiliated Hospital of Yangtze University from January 2013 to June 2018 was\nconducted to analyze the etiology, clinical manifestations and treatment of\ndifferent age groups. Results: Symptomatic epilepsy is high in the elderly, and\nmen are more than women. Among the 1170 patients with symptomatic epilepsy,\nthere were 81 (6.9%) cases of brain injury, 721 (61.6%) cases of cerebrovascular\ndisease, 223 (19.0%) cases of tumor, 59 (5.0%) cases of central\nnervous system infection, 33 (2.8%) cases of immune metabolic disease, 11\n(0.9%) cases of drugs, 6 (0.5%) cases of cortical dysplasia, 6 (0.5%) cases of\nneurodegenerative disease, 4 (0.3%) cases of parasites, 4 (0.3%) cases of poisons,\nand 22 (1.9%) cases of other diseases. Among them, central nervous\nsystem infection and cerebrovascular disease ranked first among the patients\naged 0 - 18 years, followed by immune metabolic diseases; cerebrovascular\ndisease ranked first among the patients aged 19 - 39 years, followed by tumors\nand brain trauma; cerebrovascular disease ranked first among the patients\naged 40 - 65 years, followed by tumors and brain trauma; cerebrovascular\ndisease ranked first among the patients aged over 65 years, followed by tumors,\namong the types of seizures, 74 (6.3%) cases of tonic seizures, 68 (5.8%)\ncases of clonic seizures, 856 (73.2%) cases of tonic-clonic seizures, 27 (2.3%)\ncases of myoclonic seizures, 12 (1.0%) cases of absence seizures, 116 (9.9%)\ncases of complicated partial seizures, and 17 (1.5%) cases of partial seizures,\nin addition to the etiology, 795 (67.9%) cases of sodium valproate, 152\n(13.0%) cases of carbamazepine, 56 (4.8%) cases of topiramate, 117 (10.0%)\ncases of levetiracetam, 23 (2.0%) cases of lamotrigine, and 27 (2.3%) cases of\nothers were taken. Conclusion: In symptomatic epilepsy, different age groups\nhave different causes. Among them, cerebrovascular disease, central nervous\nsystem infection, brain trauma, and brain tumor are the main causes. The\nmost common type of seizures is the occurrence of tonic-clonic seizures. The\nmost common drugs are sodium valproate and carbamazepine.
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